I-China yenza impumelelo ekuvimbeleni isifo se-virus se-Solanaceae

I-China yenza intuthuko ekuvimbeleni isifo segciwane i-Solanaceae ngemuva kokusebenzisa i-dsRNA nano nucleic acid drug, ngokusho kwe-Chinese academy of science science.

Ithimba lochwepheshe lasebenzisa ama-nanomaterials ngendlela entsha ukuthwala ama-nucleic acid ngomgoqo we-pollen, lilethe i-dsRNA ngaphandle kosizo lwangaphandle, kanye nokwenza kusebenze i-RNAi ngemva kokulethwa ezinhlayiyeni zempova ukuze kuncishiswe ukuthuthwa kwegciwane embewini.

Ukusetshenziswa kwe-dsRNA nanoparticles ekulawuleni izinambuzane kuthathwa njengobuchwepheshe obushintshayo emkhakheni wokuvikela izitshalo esikhathini esizayo.

Eminyakeni yamuva nje, leli qembu lizibophezele ekuthuthukiseni amasu okuvimbela nokulawula okuluhlaza ezinambuzane nezifo, futhi lenze ucwaningo oluhlelekile mayelana nokuhloswe ngokunembile nokuhambisana nemvelo.

Ucwaningo luqhathanise imiphumela ye-antiviral yezindlela ezine zokuletha i-dsRNA ezitshalweni, okuwukungena, ukufutha, ukucwiliswa kwezimpande, kanye nokufaka impova ngaphakathi.

Futhi imiphumela ikhombisa ukuthi i-HACC-dsRNA NPs ye-biocompatible ingasetshenziswa njengevekhtha yokuthutha ye-biomolecular elula, futhi nanjengesithwali esingase sibe khona sokuxhashazwa kwezimpawu zezitshalo ezingaguquki. Ukudluliswa kwezifo ezibangelwa amagciwane ezitshalweni kungancishiswa, ngaleyo ndlela kwehlise izinga lokuthwala igciwane lembewu yenzalo ngokufaka impova ngaphakathi ngama-NP.

Le miphumela ikhombisa izinzuzo zobuchwepheshe be-RNAi obusekelwe kuma-NPs ekuzaleni ukumelana nezifo futhi ithuthukise amasu amasha okuzalanisa izifo zezitshalo.

Lo mbiko wethulwe futhi ku-ACS Applied Materials & Interfaces, enye yephephabhuku eligunyazwe kakhulu e-China.

Nazi ezinye izibulala-zinambuzane ukuvimbela izinambuzane on yemifino.

Dimethoate 40% EC

Deltamethrin 2.5% EC