Imodi yesenzo kanye nentuthuko ye-glyphosate

I-Glyphosate uhlobo lwe-herbicide ye-organic phosphicide nge-ebrompas spectrum extereting. I-Glyphosete ikakhulukazi ithatha imiphumela ngokuvimba i-biosynthesis ye-aromatic amino acid, okungukuthi i-biosynthesis ye-phenylalanine, i-tryptophan kanye ne-tyrosine nge-shikimic acid payway. Inomthelela ovimbayo ku-Enolyruvylshikate-3-phosphate syntase (epps synthase), ekwazi ukuguqula ukuguqulwa phakathi kwama-shikate-3-phosphate kanye ne-5-phosphate phosphate ku-5-EnolPyruvyshikate-3-phosphate (ePPPPETE Interfere Ngale biosynthesis yokuphendula kwe-enzymatic, okuholela ekuqothulweni kwe-shikimic acid eVivo. Ngaphezu kwalokho, i-glyphosate ingakwazi futhi ukucindezela ezinye izinhlobo zama-enzyme wesitshalo kanye nomsebenzi we-enzyme wesilwane. I-metabolism ye-glyphosate ezitshalweni eziphakeme ihamba kancane futhi ihlolwe ukuthi i-metabolite yayo i-aninomethylphosphosphonicphon acid ne-methyl amino acetic acid. Ngenxa yokusebenza okuphezulu okusebenzayo, ukucekelwa phansi okusheshayo, kanye nobumsulwa bezitshalo eziphezulu ze-glyphose eMzimbeni Wezitshalo, i-glyphosate ibhekwa njengohlobo lokulawula ukhula olungapheli lwe-Hervicides.Glyphosate lisetshenziswe kabanzi ngenxa yezinzuzo ezingezona zokukhetha eziqinile Futhi umphumela wokukhula kahle, ikakhulukazi ngendawo enkulu yokutshala izilimo ze-glyphosate-ebekezeleleka, sekuphenduke umfelomu osetshenziswa kakhulu emhlabeni.

Ngokusho kokuhlola kwe-PMRA, i-Glyphosate ayinalo i-genotoxicity futhi mancane amathuba okubangela ubungozi bomdlavuza kubantu. Akunangozi empilweni yabantu kulindeleke ngokuhlolwa kokudalulwa kokudla (ukudla namanzi) okuhlotshaniswa nokusetshenziswa kwe-glyphosate; Landela imiyalo yelebula, futhi asikho isidingo sokukhathazeka ngohlobo lomsebenzi usebenzisa i-Glyphosate noma ubungozi kubahlali. AKUKHO ubungozi emvelweni obulindelwe uma busetshenziswa ngokuya ngelebula ebukeziwe, kepha i-buffer yesifutho iyadingeka ukunciphisa ingozi engaba khona yokufafaza ezinhlotsheni ezingahlosiwe (imifino, ama-invertebrates asemanzini kanye nezinhlanzi eduze kwendawo yesicelo).

Kulinganiselwa ukuthi ukusetshenziswa komhlaba wonke kwe-Glyphosate kuzoba ngu-600,000 ~ 750,000 t ngo-2020, kanti kulindeleke ukuthi kube ngu-740,000 ~ 920,000 t ngo-2025 ~ 920,000 t ngo-2025, okukhombisa ukukhuphuka okusheshayo.