Mokhoa oa ts'ebetso le nts'etsopele ea glyphosate

Glyphosate ke mofuta oa herbicide ea organic phosphine e felisang mefuta e mengata. Glyphosate e nka litlamorao haholo ka ho thibela biosynthesis ea amino acid e nkhang hamonate, e leng biosynthesis ea phenylalanine, tryptophan le tyrosine ka tsela ea shikimic acid. E na le phello e thibelang ho 5-enolpyruvylshikimate-3-phosphate synthase (EPSP synthase), e ka susumetsang phetoho pakeng tsa shikimate-3-phosphate le 5-enolpyruvate phosphate ho 5-enolpyruvylshikimate-3-phosphate (EPSP), kahoo glyphosate e kena-kenana. ka biosynthesis ena ea karabelo ea enzymatic, e bakang ho bokellana ha shikimic acid ka har'a vivo. Ntle le moo, glyphosate e ka hatella le mefuta e meng ea li-enzyme tsa semela le ts'ebetso ea enzyme ea liphoofolo. Metabolism ea glyphosate limeleng tse phahameng e lieha haholo mme e lekoa hore metabolite ea eona ke aminomethylphosphonic acid le methyl amino acetic acid. Ka lebaka la ts'ebetso e phahameng ea ts'ebetso, ho senyeha butle, hammoho le chefo e phahameng ea limela ea glyphosate 'meleng oa limela, glyphosate e nkuoa e le mofuta o motle oa ho laola li-perennial herbicides. le phello e ntle ea mofoka, haholo-holo ka sebaka se seholo sa ho lema lijalo tse sa pheleng tsa glyphosate, e se e le sebolaea-lehola se sebelisoang ka ho fetisisa lefatšeng.

Ho latela tlhahlobo ea PMRA, glyphosate ha e na genotoxicity mme ha e na monyetla oa ho baka kotsi ea mofetše ho batho. Ha ho kotsi ho bophelo ba batho e lebeletsoeng ka litlhahlobo tsa ho pepeseha ha lijo (lijo le metsi) tse amanang le tšebeliso ea glyphosate; Latela litaelo tsa label, 'me ha ho na lebaka la ho tšoenyeha ka mofuta oa mosebetsi o sebelisang glyphosate kapa kotsi ho baahi. Ha ho kotsi tikolohong e lebelletsoeng ha e sebelisoa ho latela leibole e ntlafalitsoeng, empa setlolo sa sefafatsi sea hlokahala ho fokotsa kotsi e ka bang teng ea ho fafatsa mefuta e sa lebelloang (limela, liphoofolo tse phelang metsing le litlhapi tse haufi le sebaka sa kopo).

Ho hakanngoa hore ts'ebeliso ea lefats'e ea glyphosate e tla ba 600,000 ~ 750,000 t ka 2020, 'me e lebelletsoe ho ba 740,000 ~ 920,000 t ka 2025, e bonts'ang keketseho e potlakileng. Kahoo glyphosate e tla lula e le eona e bolaeang litlama nako e telele.