Ụdị omume na mmepe nke glyphosate

Glyphosate bụ ụdị ahịhịa ahịhịa phosphine organic nwere ụdị dị iche iche na-ekpochapụ. Glyphosate na-ebutekarị mmetụta site na igbochi biosynthesis nke amino acid aromatic, ya bụ biosynthesis nke phenylalanine, tryptophan na tyrosine site na ụzọ shikimic acid. Ọ nwere mmetụta mgbochi na 5-enolpyruvylshikimate-3-phosphate synthase (EPSP synthase), nke nwere ike ime ka mgbanwe dị n'etiti shikimate-3-phosphate na 5-enolpyruvate phosphate n'ime 5-enolpyruvylshikimate-3-phosphate (EPSP), ya mere glyphosate na-egbochi ya. site na biosynthesis nke mmeghachi omume enzymatic, na-ebute mmụkọ shikimic acid na vivo. Na mgbakwunye, glyphosate nwekwara ike igbochi ụdị enzymes osisi ndị ọzọ na ọrụ enzyme anụmanụ. Metabolite nke glyphosate na osisi ndị dị elu na-adị ngwa ngwa ma nwalee na metabolite ya bụ aminomethylphosphonic acid na methyl amino acetic acid. N'ihi na nke elu na-arụ ọrụ arụmọrụ, ngwa ngwa mmebi, nakwa dị ka nnukwu osisi toxicity nke glyphosate na osisi ahụ, na glyphosate na-ahuta dị ka ụdị ezigbo ịchịkwa perennial igbo herbicides.Glyphosate e ọtụtụ-eji n'ihi na nke uru nke ike na-abụghị nhọrọ. na mmetụta ahịhịa dị mma, ọkachasị na nnukwu ebe a na-akọ ihe ọkụkụ nke glyphosate na-anabata transgenic, ọ ghọwo ahịhịa ahịhịa kacha eji eme ihe n'ụwa.

Dị ka nyocha PMRA si kwuo, glyphosate enweghị genotoxicity na o yikarịrị ka ọ ga-ebute ọrịa cancer na ụmụ mmadụ. Enweghị ihe ize ndụ maka ahụike mmadụ ka a na-atụ anya site na nyocha ikpughe nri (nri na mmiri) jikọtara ya na iji glyphosate; Soro ntuziaka labelụ, na ọ dịghị mkpa ichegbu onwe gị banyere ụdị ọrụ na-eji glyphosate ma ọ bụ ihe ize ndụ nye ndị bi. Ọ dịghị ihe ize ndụ na gburugburu ebe obibi a na-atụ anya mgbe ejiri ya dị ka akara nke edegharịrị, ma a na-achọ ihe nchekwa mmiri iji belata ihe ize ndụ nke ịgbasa na ụdị ndị na-abụghị ihe (osisi, invertebrates aquatic invertebrates na azụ dị n'akụkụ ebe ngwa ngwa).

A na-eme atụmatụ na iji glyphosate zuru ụwa ọnụ ga-abụ 600,000 ~ 750,000 t na 2020, a na-atụkwa anya na ọ ga-abụ 740,000 ~ 920,000 t na 2025, na-egosi mmụba ngwa ngwa. Ya mere glyphosate ga-anọgide na-abụ isi ihe ọkụkụ ruo ogologo oge.